AI幫忙! 全新抗生素 可抗超級細菌 - 股票QA

By Yedda
at 2023-05-27T14:29
at 2023-05-27T14:29
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原文標題:
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AI幫忙! 全新抗生素 可抗超級細菌
原文連結:
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https://news.ltn.com.tw/amp/news/world/paper/1585173
發布時間:
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2023/05/27 05:30
記者署名:
※原文無記載者得留空
林雨萱
原文內容:
科學期刊「自然─化學生物學」(Nature Chemical Biology)廿五日刊登的研究顯示,加拿大麥馬斯特大學和美國麻省理工學院的一群科學家利用人工智慧(AI),發現一種全新抗生素Abaucin,可用於對抗被世界衛生組織列為「重大威脅」的超級細菌「鮑氏不動桿菌」(Acinetobacter baumannii)。科學家表示,AI能夠大幅加速新藥物的研發,此為AI推動科學和醫學變革的最新案例。
鮑氏不動桿菌會造成肺炎、腦膜炎和其他嚴重感染,對需要呼吸器與血液導管,以及開放性傷口的患者構成生命威脅。美國疾病管制中心指出,這種細菌還會「定殖」或生存在患者體內,卻又不會引發感染或病徵。協助主導研究的麥馬斯特大學生物醫學及生物化學系助理教授史托克斯表示,鮑氏不動桿菌是頭號公敵,幾乎對每一種抗生素都具有抗藥性。
抗生素能夠殺死細菌,然而,數十年來新型藥物的缺乏,加上細菌不斷演化出抗生素抗藥性的特性,估計每年有逾一百萬人因此死亡。為了要找到有效對付鮑氏不動桿菌的抗生素,科學家首先利用AI分析六六八○種現存藥物的結構能否阻止鮑氏不動桿菌繁殖,或是殺死它。僅花費一個半小時,AI就挑出可能有效的二四○種藥物,再由科學家透過實驗從中篩選出九種,最後找到最有效的Abaucin。
精準對抗鮑氏不動桿菌 降低抗藥性
實驗結果顯示,Abaucin能用於治療老鼠身上的傷口感染,而且能殺死病患身上的鮑氏不動桿菌樣本。史托克斯說,下一步是要讓這項藥物更加完善,接著進入臨床實驗階段,期待第一款AI抗生素能夠在二○三○年上市。
許多抗生素能一網打盡多種細菌,但Abaucin只能用於鮑氏不動桿菌,無法殺死其他細菌。科學家認為,Abaucin對抗病毒的準確性,能提升細菌演化出抗藥性的難度,產生的副作用也較少。
心得/評論:
※必需填寫滿30字,無意義者板規處分
Ai不只會挑土豆 還會精準打擊
皮衣刀客這波要變成乘龍快婿了吧
美時會變成ai 股嗎 唉呦我去
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